PhysioCue's 2.0
Hypertension Reduction Therapy Device

PhysioCue's 2.0 Hypertension Reduction Therapy Devices externally stimulate carotid baroreceptors, which are located within the carotid sinus in the neck, using our hand-held therapy device with our patented cold tip. Cold temperature stimulation of the baroreceptors, at a precise temperature and duration, results in modulating the autonomic nervous system, stimulating the parasympathetic nervous system, and lowering the sympathetic drive, causing vasodilation and lowering of the heart rate.

The sum of these actions results in immediate lowering of blood pressure.

In PhysioCue's proof-of-concept pilot clinical trial conducted with PhysioCue's 1.0 device, in a panel of 60 patients over 68 days, a typical patient had a systolic BP of 176mmHg. After the patient's first 5-minute PhysioCue therapy session, BP dropped to 155mmHg. Daily 5-minute therapy sessions produced similar results, and the patient's sustainable BP steadily dropped to 134mmHg - a total reduction of 42mmHg over 68 days.

The same clinical trial showed that daily use of the 1.0 device, for 30 to 35 days, can result in 24-hour sustained lowering of BP, which indicates that the parasympathetic part of the autonomic nervous system has been conditioned to maintain vasodilation and the lower heart rate.

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